Randomized controlled trial on dysgeusia-specific acupuncture: Results published
Chemotherapy-induced taste alterations are are a frequent side effect, and for many patients they influence appetite, nutrition, and quality of life.
In our recently published randomized controlled trial, we explored dysgeusia-specific acupuncture over 8 weeks combined with self-acupressure for cancer patients experiencing both chemotherapy-induced dysgeusia and cancer-related fatigue. Because the planned sample size was not reached, the data were analyzed exploratorily. No relevant group differences were observed.
However, the intervention design of this study is notable. Both the intervention and control groups received a combined intervention consisting of acupuncture and self-acupressure. Patients in the intervention group received additional dysgeusia-specific treatment, while patients in the control group received an intervention focused solely on cancer-related fatigue.
The inclusion of self-acupressure shows how integrative medicine can support patient-centered symptom self-management beyond the clinical setting.
Furthermore, analyzing and reporting data from studies that did not reach the planned sample size is important, as it makes the available evidence accessible for future systematic reviews and evidence syntheses.
Full publication (open access)
Huber C, Zhang L, Schlaeppi M, et al. Acupuncture in chemotherapy-induced dysgeusia (AcuDysg): study protocol of a randomised controlled trial. BMJ Open 2023;13:e066137.